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Species differences might account for some of the variability of results concerning the efficacy of the various agents

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In injured nerves, MMP2 (gelatinase A, or 72 kDa type IV collagenase), MMP3 (stromelysin1) and MMP9 (gelatinase B, or 92 kDa type IV collagenase) have been found upregulated (La Fleur et al., 1996

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doi: 10.2174/0929867013372616

The Xamoterol in Severe Heart Failure Study Group