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Yang et al., An ROS-responsive artesunate prodrug nanosystem co-delivers dexamethasone for rheumatoid arthritis treatment through the HIF-1/NF-B cascade regulation of ROS scavenging and macrophage repolarization

ADVERSE REACTIONS: Adverse reactions other than those indicative of hyperthyroidism because of therapeutic overdosage, either initially or during the maintenance period, are rare (See OVERDOSAGE)

The absorbance was measured using a spectrophotometer at 536 nm at 10 min intervals for 1 h

A physiological role for SOD1 in guarding against mitochondrial oxidative damage

However, injections must go through muscle tissue, which may not be as effective as intravenous injections

In contrast, low-burden, late-forming granulomas are associated with a response involving cytotoxic T cells and type 1-type 17 immunity (193)
