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Congenital NEMO Alteration at Position 223 causes Ectodermal Dysplasia and Immunodeficiency with Normogammaglobulinemia

LPS, particularly its lipid A portion, is actually toxic

Using this approach, we identified monocytes with cytosolic ASC speck formation associated with active caspase-1/4/5, represented by FLICA + ASC-speck + cells ( Figure 2C , Merge panel)

Antioxidants also support the prooxidant chemistry that demonstrate chemotherapeutic potential, particularly at high or pharmacological doses and trigger OS by promoting free radical production, which is essential for activating cell death pathways

F., Cabrini, M

externally peer reviewed