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Inpatients (i.e., more severely depressed patients) may be given up to but not in excess of 600 mg/day in divided doses Once an adequate response has been achieved, dosage may be gradually reduced, with subsequent adjustment depending on therapeutic response

NO is a retrograde messenger in dopaminergic synapses

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Too little, and you see no results

You do not need elaborate programs

How Quickly Does a B12 Shot Work Many people feel the effects of a B12 shot within 24 to 72 hours, especially if they were deficient