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The Evidence Base: What Human and Animal Studies Actually Show Translating rodent data to human protocols requires caution, but the MOTS-c literature offers enough cross-species convergence to draw meaningful clinical inferences

J., Gurieva, I., Low, P

[DOI] [PubMed] [Google Scholar] 55.Joshi P.K., Patel S.C., Shreya D., Zamora D.I., Patel G.S., Grossmann I., Rodriguez K., Soni M., Sange I

3 (eds Hamilton, K

Keap1 adduct formation changes the conformation of Keap1, leading to the Keap1-Nrf2 dissociation, as well as leading to Keap1 ubiquitination and degradation [37]
doi: 10.1038/s41467-023-40182-4
