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Data availability Data is provided within the manuscript or supplementary information files

Dysbiosis and increased intestinal permeability (leaky gut) may amplify neuroinflammatory state of the brain, further justifying the need for research into interventions combining metabolic and microbiota-based therapies

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LGSH derived from MGO is subsequently hydrolyzed by glyoxalase 2 (GLO2) to produce D-lactate and glutathione [33]

Shaik MS, Haynes A, McSween J, Ikediobi O, Kanikkannan N, Singh M

It is important to consult with a healthcare professional before using curcumin or any other supplement for UFs to ensure it is safe and appropriate for the individuals circumstances
