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We performed a Spearman correlation coefficient analysis to highlight the interactions between intestinal microbiota-serum factors and intestinal microbiota-metabolites. Results: XJP contains 91 compounds that alleviate pathologies of BPH in rats, decreasing prostate weight, index, and serum levels of Dihydrotestosterone (DHT), Prostate-Specific Antigen (PSA), epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF) levels

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Shekaran A, Garcia JR, Clark AY, Kavanaugh TE, Lin AS, Guldberg RE, et al

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This enabled commercial use even without full drug approval