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This heterogeneity necessitates a multi-pronged therapeutic strategy

Taken together, the literature indicates that while both CHAC1 and CHAC2 participate in related biological processes, their different structural and regulatory properties suggest complementary rather than redundant functions

Further validations in terms of specificity, sensitivity, and reproducibility in larger populations (including children as well) will be required for these new markers before applications in routine clinical practice

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Stratification of astrocytes in healthy and diseased brain