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Keywords: antioxidants, oxidative stress, sepsis, infection, cysteine Oxidative damage and antioxidant defense, inflammation, and immunity Reactive oxygen species and oxidative stress While the oxidative deterioration of lipids has been known for a long time, it was only in the late 1960s that we became aware of the importance of these chemical processes in pathology and toxicology with the finding that lipid peroxidation or rancidification occurred also in biological systems

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We also acknowledge the use of the BSL3 facilities from Servicio General de Apoyo a la Investigacin-SAI of the University of Zaragoza

Although much remains to be done to definitively establish NAC in some of the conditions considered in this review, this molecule has a number of properties that make it an ideal adjunctive treatment to established therapies for complex diseases, including a favorable pharmacokinetic profile with few relevant drug-drug interactions

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The Coffee and Glutathione Connection Now that we have a solid understanding of glutathione, lets explore the interaction between coffee and this vital antioxidant