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This "phospholipid bilayer" (a double layer of healthy fats) acts as a protective shield around the glutathione

J.SuT.HibshooshH.et al

Comparison of the effects of deferasirox, deferiprone, and deferoxamine on the growth and virulence of Vibrio vulnificus

Thus, although GTK probably contributes to the bioactivation of toxic halogenated cysteine S -conjugates in the rat kidney, other cysteine S -conjugate -lyases presumably play an important role in the mitochondrial damage

FIGURE 1 Ferroptosis appears to require the presence of specific highly oxidisable phosphatidylethanolamine phospholipids containing the polyunsaturated fatty acids (PUFAs) arachidonic acid and adrenic acid

[PubMed: 23009777] 552