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W Scott S: Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival

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For the last two decades, skeletal muscle was the main target of therapy [40], and drug discovery programs focused on strategies to inhibit the muscle catabolic pathways and stimulate the anabolic pathways [52]

Additionally, fiber-rich diets and probiotics encourage a gut microbiome that is less conducive to TMA production [81]

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[DOI] [PubMed] [Google Scholar] 76.Wingfield PT, Stahl SJ, Thomsen DR, Homa FL, Booy FP, Trus BL, et al