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In a study with 77 Japanese patients with INH + rifampicin treatment, the risk of liver injury was much higher in slow acetylators than in intermediate and rapid acetylators 78

The p62-Keap1-NRF2 pathway plays an important role in preventing ferroptosis in HCC cells, and the RAS/Raf/MEK pathway is an important target for the treatment of HCC 32,40

Acknowledgements The authors thank all the oncologists in the radiation center for their support and help throughout the study

doi: 10.1016/j.glmedi.2024.100081 [DOI] [Google Scholar] 5.Uddin TM, Chakraborty AJ, Khusro A, et al

van der Worp HB, Howells DW, Sena ES et al (2010) Can Animal Models of Disease Reliably Inform Human Studies

Cell diversity and network dynamics in photosensitive human brain organoids