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doi: 10.1002/jcp.21626
S2CID 30838296
In the specific context of SCI, local ischemia and anoxia caused by trauma, together with the subsequent inflammatory response and surge of oxidative stress, lead to excessive activation of endoplasmic reticulum stress in spinal cord neurons and glial cells
Concentration and Reconstitution Factors Highly concentrated solutions may increase localized irritation potential in some biological models

A 30-second verification step eliminates the largest single risk factor in peptide use

Zhu et al., 1999a)