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How it works: TB-500 is a synthetic fragment of Thymosin Beta-4, a protein your body uses to move healing cells to damaged areas and build new blood vessels

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37 Small molecule GLP-1RAs are chemically synthesized, and compared to protein-based drugs, they generally have smaller molecular sizes

Furthermore, most PLGA nanoparticles are synthesized utilizing solvent evaporation method, rendering it difficult to be reproduced at large scale under good manufacturing practice (GMP) conditions 110,147

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Another key feature of this study is the use of full-length CSD and subregions modified to be water-soluble, thereby enhancing the likelihood they can be developed to treat human disease