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This review systematically summarized LC-associated psychological symptoms, including social stigma and shame, anxiety and depression, PTSD, fatigue, sleep disturbances, and cognitive dysfunction, all of which significantly reduce patients quality of life and social functioning

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Treatment of L-serine also significantly downregulated 195 genes and upregulated 136 genes in the IL7R low naive CD4 T cell subtype of the patients (Supplementary Data 2)

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