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In addition to its participation in the WWC, ascorbate is also required for the regeneration of lipid-soluble antioxidants, particularly tocopherols and tocotrienols (vitamin E), which protect the polyunsaturated fatty acids in the thylakoid membranes from oxidation to chromanoxyl radicals by singlet oxygen

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When that happens, the molecule loses its biological activity

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If you follow a vegan or vegetarian diet, are over the age of 50 , or live with a digestive condition like Crohns disease or pernicious anaemia, your body might struggle to absorb B12 from your food