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That enzyme is NNMT, nicotinamide N-methyltransferase

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AOD 9604 is a synthetic 16-amino-acid fragment of human growth hormone (residues 176191), developed for studying fat and energy metabolism

The cartilage finding is notable because it suggests the peptide acts through pathways relevant to connective tissue repair, not only lipolysis

Ulanovskaya OA, Zuhl AM, Cravatt BF. NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. Nat Chem Biol. 2013 May;9(5):300-6. doi: 10.1038/nchembio.1204. Epub 2013 Mar 3. PMID: 23455543; PMCID: PMC3631284