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Symptoms typically progress through stages, starting with mild signs and potentially leading to more severe complications if left untreated

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10.1016/j.cell.2013.10.045 98

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Oxygen sensing by T cells establishes an immunologically tolerant metastatic niche

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Erythropoietic protoporphyria Erythropoietic protoporphyria, in which protoporphyrin accumulates in the bone marrow, red blood cells, or blood plasma, causes skin hypersensitivity to light (i.e., photosensitivity)

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