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Importantly, recent studies indicate that deficiency in Prx6-dependent selenium delivery can significantly decrease GPX4 protein level, with a corresponding reduction in ferroptosis sensitivity of similar magnitude
& Spray, D
doi: 10.1001/jama.281.8.727
Selenium and iron, two elemental rivals in the ferroptotic death process
They have to be taken with fluids to work
Excessive production of free radicals damages the bodys antioxidant defense system, and has toxic effects, which cause OS (Halim and Halim, 2019) (Spinelli and Haigis, 2018) (Sergi et al., 2019)
