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Furthermore, the review notes the immunomodulatory role of two relatively underexplored compounds, acrylamide and maltol

ADH = Antidiuretic hormone (vasopressin) ARBs = Angiotensin receptor blockers BBB = Blood brain barrier BKN = Bradykinin CFS = Chronic Fatigue Syndrome COMT = Catechol-O-methyltransferase CRH = Corticotropin-releasing hormone CVOs = Circumventricular organs DAO = Diamine oxidase EDS = Ehlers Danlos syndrome FB = Fibromyalgia Glu = Glutamate GnRH = Gonadotropin releasing hormone Hcy = Homocysteine HNMT = Histamine N-methyltransferase HPA = Hypothalamus-pituitary-adrenal LC = Long COVID MCAS = Mast cell

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The participants diets were supplemented with either 1 g of LC-L-tartrate and 3 g of leucine per day (LC group) or 4 g of leucine per day as a placebo (PLA group), in a double-blind fashion