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Although the causal relationship between smoking and the pathogenesis of AA has not been fully established, cigarette smoke has been shown to promote the production of proinflammatory cytokines while decreasing levels of anti-inflammatory cytokines (Dai et al., 2020)

PMID: 23 MeyerKCRaghuGBaughmanRPBrownKKCostabelUdu BoisRMet al

Zhu YC, Elsheikha HM, Wang JH, Fang S, He JJ, Zhu XQ, Chen J

doi: 10.1016/j.ijantimicag.2019.09.008 485 ZhenC.WangL.FengY.WhitewayM.HangS.YuJ.et al

(2025) Furthermore, multiple studies have demonstrated that lipid-lowering medication use exerts potentially beneficial effects on AMD prevalence, reducing AMD risk by 35-50% [139, 140]
We never lose sight of the fact that, first and foremost, our goal is to optimize the treatment of each individual patient