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However, recent evidence suggests that the GH produced locally by the colon tumor cells, and not pituitary GH, acts in an autocrine and paracrine manner to suppress the tumor suppressor proteins and to increase nuclear -catenin accumulation and epithelialmesenchymal transition potentially participating in tumor progression (46,47)

In order to identify a second putative endogenous photosensitizer, fluorescence emission and excitation spectra were performed on bacteria extracts