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Unlike many therapeutic compounds, BPC-157 does not exist as a complete molecule in nature but rather represents a stable, active fragment of a larger protective protein

10.1038/srep08510 [DOI] [PMC free article] [PubMed] [Google Scholar] 49.Fenech M (1999) Micronucleus frequency in human lymphocytes is related to plasma vitamin B12 and homocysteine

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It is likely that mitochondrial biogenesis is an indirect response to improvement in B12 availability, recognizing that the two enzymes to which B12 is a co-factor are both linked to mitochondrial metabolism

Metformin improves outcomes by treating NAFLD/NASH to delay the progression to cirrhosis and inhibits hepatic fibrosis (62)