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Glutathione neutralizes the reactive oxygen species that trigger NF-B-mediated inflammatory cascades, reducing inflammatory burden at the cellular level

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doi: 10.1016/j.biomaterials.2022.121799 131 HuangMMyersCRWangYYouM

60 Roflumilast, as the most used PDE-4 inhibitor, was indicated as a treatment choice to improve lung function and reduce the risk for exacerbations in patients with severe COPD (GOLD patient groups C and D)

The presence of this resistance marker at high frequency in Obout supports previous observation in northern Cameroon (Gounougou) by Menze et al