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Once the pathway is disrupted, senescent cells undergo programmed cell death while healthy cells remain protected

24 GaoT.ChenZ.ChenH.YuanH.WangY.PengX.et al (2018)

New revolution for quality control of TCM in industry 4.0: focus on artificial intelligence and bioinformatics
In hypertrophic and failing myocardium, the level of SERCA2 protein and its ability to absorb Ca 2+ are inhibited

10.1007/s10911-008-9104-6 [DOI] [PMC free article] [PubMed] [Google Scholar] Wu T., Qi W., Shan H., Tu B., Jiang S., Lu Y., et al

CBS deficiency led to markedly homocysteine accumulation and severely decreased levels of cystathionine and cysteine, which was due to impaired homocysteine removal through the transsulfuration pathway [32]