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This preliminary reaction stage is designed to activate the phenylboronic acid for subsequent conjugation

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Results : In the series 350 cases380 KNEES of taking into consideration the severity of OA as per K&J classificationGrade 2 (minimal) moderate joint reduction, Grade 3 (moderate) severe joint space reduction with subchondral sclerosis, Grade 4 (severe) large osteophytes, marked narrowing of joint space, severe sclerosis and definite deformity of bone ends