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Mechanistically, intranasally administered agents may be absorbed through the olfactory epithelium or trigeminal nerve endings and transported to the brain via extracellular diffusion and intracellular axonal pathways, which may partially bypass BBB-related constraints (Raghav et al., 2023

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An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study