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However, oncology guidelines also focus on motivational encouragement to increase activity and engagement in life roles as recovery continues [64], whereas ME/CFS guidelines prioritize validating limitations and avoiding pushing patients beyond their limits [90]

doi: 10.1002/jimd.12378

Showed no significant effect on lactate, pyruvate, malate, phosphoenolpyruvate, 3-phosphoglycerate, dihydroxyacetone phosphate, -glycerophosphate, glucose-6-phosphate, citrate, isocitrate, NH4+, L-glutamate, CoA, adenine nucleotide levels, cytoplasmic NAD+/NADH ratio, or cytoplasmic and mitochondrial phosphorylation states in rats fed a 30% fat plus 20% 1,3-butanediol diet