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Metallothionein-1 (MT-1) mRNA levels were markedly elevated during exacerbations in gout patients, particularly in PBMCs from patients with gouty stones

Its interaction with the nitric oxide system is bidirectional: BPC-157 counteracts both NO-synthase inhibition and excessive NO release, effectively functioning as a stabilizer of the NO system rather than a simple agonist or antagonist

8 Strategies to improve the therapeutic effect of MSCs for IVDD and their challenges in clinical application The microenvironment plays a decisive role in MSC-mediated intervertebral disc regeneration

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