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Initially, such hyperexcitability may arise as a compensatory response to peripheral deafferentation

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All research was conducted in accordance with relevant guidelines and regulations after written informed consent was obtained from all subjects

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CZ: Conceptualization, Writing review & editing

The decline in LVDP was attenuated with 4-ClDzp, with 4-ClDzp treated hearts having significantly higher LVDP from 22 minutes after diamide through the duration of the protocol (Figure 4)