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Current research shows that HT has a protective effect on intestinal oxidative damage, which is mediated by regulating the PI3K/Akt-Nrf2 signaling pathway and mitophagy

Appl Microbiol Biotechnol 66:233242

Arteel GE, Briviba K, Sies H
25 HeidariR.BabaeiH.EghbalM
S1PR2 inhibitors potently reverse 5-FU resistance by downregulating DPD expression in colorectal cancer

In fact, recent evidences suggest a role for PTTG1 in the induction of EMT
