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Self-administration of PCT medicines was reported by 73% of men discontinuing AAS in Scotland between 2015 and 2022 (Grant et al., 2023a) and by 80% of 100 male athletes in the Netherlands between 2015 and 2018 (Smit et al., 2021)

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In the empatic-360 group, 82.6% of patients lost at least 5% of their baseline body weight and 47.7% lost at least 10% of their baseline body weight as compared to 18.9% and 5.7% patients in the placebo group, respectively [192]

According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections