glutathione and alpha-lipoic acid patrick 2002 Regeneration of by α-lipoic via Nrf2/ARE signaling pathway alleviates cadmium-induced HepG2 cell toxicity Alpha Lipoic Acid: Benefits, Forms,

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Meta-analysis of vitamin C concentrations in plasma The analyzed data from the selected studies showed that plasma vitamin C levels are significantly reduced in the AD patients as compared to the healthy controls (pooled SMD with random-effect model: 1.164, with 95%CI: 1.720 to 0.0608, Z = 4.102, p = 0.00)

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High plasma levels were effectively associated with increased plasma and lymphocyte SAH and a decreased SAM to SAH ratio that could negatively affect cellular methylation potential (Fu et al, 2000