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It was engineered isolate hGHs lipolytic (fat-breaking) properties without activating the growth hormone receptor or increasing IGF-1. The design allows it to mimic hGHs metabolic domain in a shorter, more stable form

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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Moreno-Navarrete JM, Ortega FJ, Rodriguez-Hermosa JI, Sabater M, Pardo G, Ricart W, Fernandez-Real JM

The weight maintenance after tirzepatide guide addresses the related question of sustaining results during and after the transition off active treatment