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Yang Y, Luo L, Cai X, Fang Y, Wang J, Chen G, et al
FIGURE 10 10 Metal chelators Various chelating agents have been used to inhibit metal-dependent oxidative damage
DNA Methylation Biomarkers in Colorectal Cancer: Clinical Applications for Precision Medicine
Gastroenterology 156 , 1264-1281 e1264
Specifically, the base excision repair (BER) pathway employs enzymes like thymine DNA glycosylase (TDG) to recognize and excise 5caC, creating a basic site (44)
Alternatively, NAC could be converted to cysteine by aminoacylases in the kidney or other tissues [31] with cysteine actively transported across the BBB [32]
