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10.3748/wjg.v28.i25.2843 2 AlberghinaM.LupoG.La SpinaG.MangiameliA.GulisanoM.SciottoD.et al (1992)

Therefore, these effects are not only local, but the microenvironment that is created maintains M1 activation leading to further, widespread damage

most of the existing studies are observational or animal experiments, and it is difficult to extrapolate them directly to humans

While presenting symptoms are often vague, anorexia (loss of appetite), dehydration, weight loss and lethargy may be observed

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