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HIF-1 upregulates the expression of glycolytic enzymes and glucose transporters, increasing glucose uptake and its diversion into the PPP (139)

Proteomics 18 , 818836 (2019)

International journal of preventive medicine 7 Patwa J, Khan S, Jena G (2020) Nicotinamide attenuates cyclophosphamide-induced hepatotoxicity in SD rats by reducing oxidative stress and apoptosis

This offers an alternative method to preserve de novo fatty acid synthesis during hypoxic conditions through the regulation of glutaminase 1 (GLS1), glutamate dehydrogenase 1 (GLUD1), and isocitrate dehydrogenase 1 (IDH1) by HIF-1 [55,56]

Pattison, D
