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Likewise, MPTP is metabolized into the toxic cation 1-methyl-4-phenylperydinium (MPP + ) [156] by the enzyme MAO-B of glial cells, specifically astrocytes, provides that high-affinity for MPP + affects dopamine transporter (DAT)

For older adults who are already deficient, taking one milligram of vitamin B12 daily for a month has been shown to reverse the deficiency and appears to be safe and without side effects

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