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In pathophysiological states, including increased insulin resistance, the hybrid receptor number is changed significantly, thus potentially abrogating the chance for IGF-1 to alter glucose metabolism [129, 132, 133]

[DOI] [PubMed] [Google Scholar] 278.Bustos G., Moldes A.B., Manuel C.J., Domnguez J.M

In: Peixoto Basso T., Olitta Basso T., Carlos Basso L., editors
2.5 Metabolic coupling mechanisms between neurons and astrocytes Another emerging trend is the investigation of metabolic coupling between neurons and astrocytes (Ashrafi and Ryan, 2017)
130,145,146 As the closest homolog of ZIP8, ZIP14 also participates in response to sepsis and is implicated in the beneficial anti-inflammatory effects of supplemental dietary zinc during sepsis, indicating its potential as a therapeutic target

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