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The explanation does not stem from a variance in IONP penetration into promastigotes and amastigotes, as both life forms were observed to successfully accumulate these particles (201)

All data presented are representative of at least three independent experiments, as indicated in the figure legends, along with the number of biological replicates

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425,489,490,491 In a word, extensive breakthrough upon lactate targeted therapy requires further research into lactate/lactylation biology, related molecular pathways, and associated interactions between consonants of TME to provide foundational support