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Phospholipids containing Oxylipins from Enzyme Reactions Fatty acids are oxidized to hydroperoxy fatty acids in animal and plant tissues by several different lipoxygenases and cytochrome P450 enzymes, which give metabolites with a high degree of positional and stereospecificity

7-KC was linked to increased ROS formation and GSH depletion in neurons, indicating oxidative stress as a key driver of cell damage (Lee et al., 2007)

Cholesterol hydroperoxides and oxysterols are more recent markers, detectable e.g., by HPLC, in combination with chemiluminescence or UV, respectively [203]

Sugar amines exhibit proton affinity and accelerate hydrolysis via an acrylic imine intermediate under mild acidic conditions through a general acid-catalyzed mechanism

Gaba induces A hormonal counter-regulatory response in subjects with long-standing type 1 diabetes

Epilepsy Research , 166 , 106409