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And heres where it gets more interesting NNMT is hyperactive in conditions like obesity & type 2 diabetes, Alzheimers & Parkinsons disease, aging in general

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Core Difference Comparison From a mechanistic perspective, the role differences between the two are very clear and can be summarized in the following table: The Relationship Between the Two: Synergistic Rather Than Antagonistic NAD+ and 5-Amino-1MQ are not in competition, but rather address the same problem from different angles-maintaining adequate intracellular NAD+ levels