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Answers to these questions will provide insights into the mechanisms of ferroptotic cell death and associated human diseases, as well as new therapeutic strategies for such diseases

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19 Gene expression differences involved in O-GlcNAcylation and hexosamine biosynthesis pathway have also been detected between diabetic and nondiabetic individuals, 20 probably because multiple molecules in insulin signaling pathways can be modified by glycosylation which in turn reduces phosphorylation, leading to inhibition of insulin signaling

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In vitro metabolism of the glucagon-like peptide-1 (GLP-1)-derived metabolites GLP-1 (9-36) amide and GLP-1 (28-36) amide in mouse and human hepatocytes