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E.ShinY

Methods Cloning, expression, and purification of human CBS proteins The gene for human CBS (UniProt P35520) was cloned into pNIC-Bsa4 and pNIC-CH encoding for a TEV cleavable N-terminal and permanent C-terminal His-tag, respectively

PD and IBD are linked to mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which is implicated in microbial immunological signaling (95)
Data from animal models of diabetes also indicate that deficiencies of neurotrophic factors and their receptors are involved in the development of diabetic neuropathy [1]

Utilizing transcriptomics, we recently reported that the loss of AGXT suppresses FAO pathways and accelerates diet-induced MASH in mice 12
