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1 Introduction Vitamin B12, or cobalamin, is a water-soluble vitamin, that plays an essential role in cellular metabolism, particularly in DNA synthesis, methylation processes, and mitochondrial functions ( Lactobacillus spp ) (LeBlanc et al., 2013), which are also found in the gastrointestinal tract of herbivorous animals, where the synthesis of B12 occurs and the vitamin can be acquired in animal tissues

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11,12 Platelets along with growth factors which are platelet-derived growth factors (PDGFs), transforming growth factor b1 (TGF- 1), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor 1(IGF-1), or fibroblast growth factor (FGF) play a critical role in cell proliferation, chemotaxis, cell differentiation, and angiogenesis

Key panels: CBC, CMP, vitamin D, B12, iron/ferritin, folate, calcium, magnesium, zinc, thyroid

Most patients describe it as a small pinch