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[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Xu Y., Guan Y., Yang X., Xia Z., Wu J
It ranges from 7.5 to 8.4 and before the Industrial Revolution the average was 8.2

But, supplements often range from 2.4 mcg to 100 mcg

The initiator of the pathophysiological process has not been elucidated yet, although acute gastrointestinal infections have been found to initiate the symptoms in a certain group of patients with IBS (post-infectious IBS) (81)

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(Please note that I am presenting a tremendous over-simplification about genetics here
