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Interestingly, these markers largely reversed in liver-specific Gclc-Nrf2 DKO mice

1 H NMR (400 MHz, DMSO-d6) = 4.78 (s, 2H), 3.52 (t, J = 7.0 Hz, 4H), 2.66 (t, J = 7.1 Hz, 4H), 1.53 (s, 6H)

AJRA, BRM, and LOM: Writingoriginal draft, Writingreview & editing, Funding acquisition

Additionally, serine-derived metabolites such as glutathione, glycine, cysteine, and SAM support phase II metabolism because they are utilized for conjugation with toxins for toxin metabolism and excretion

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