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(PubMed) Diez-Ricote L, San-Cristobal R, Concejo MJ, et al
The onset and extent of genomic instability in sporadic colorectal tumor progression
[DOI] [PubMed] [Google Scholar] 54.Bates JM, Mittge E, Kuhlman J, Baden KN, Cheesman SE, Guillemin K
With the shift towards glycolysis, there is a reduction in oxidative phosphorylation affecting the mitochondria and its function
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Figure 2 Transporters Involved in Platinum Influx/Efflux The accumulation of platinum antitumor agents inside the cells is the necessary assurance of cytotoxicity, so decreased influx or increased efflux is responsible for platinum resistance
