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Compared to patients without mitochondrial dysfunction, those with mitochondrial dysfunction exhibit impaired auditory steady-state response, worse psychopathological status, neuro-cognitive performance and global and social functioning

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Mechanisms (taking also into account components of oxidative stress) of disrupting effects of iodine excess on thyroid hormone synthesis are illustrated in Fig

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24, 25 These TJ proteins include 1 integral and transmembrane proteins, including the claudins, occludin, and junctional adhesion molecules (JAM), which extend into the intercellular spaces to regulate the gate function, and 2 cytoskeletal linker proteins, such as cingulin, ZO-1, ZO-2, and ZO-3, which anchor TJ-integral membrane proteins to cell cytoskeleton