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A deficiency in L-serine can contribute to elevated homocysteine levels through two mechanisms

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Mitochondria contribute to this balance by coupling oxidative phosphorylation (OXPHOS) to signaling: ROS generated primarily at Complexes I and III shape cytokine programs 1,2,3,4

One user reported: "I have used GHK-cu injectable and topical and found no effect on E2 or DHT." The tradeoff is that GHK-Cu doesn't address the underlying hormonal cause of androgenetic alopecia